Massachusetts Institute of Technology Postdoctoral Associate, Tonegawa Lab in Cambridge, Massachusetts

Postdoctoral Associate, Tonegawa Lab

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Research - Scientific

  • Department:

Picower Institute for Learning & Memory

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Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.

POSTDOCTORAL ASSOCIATE, Picower Institute for Learning and Memory-Tonegawa Lab, to participate in neuroscience research dissecting what happens in the brain when a memory is formed; when a memory formed previously is recalled on subsequent occasions; the role of memory in decision making; and how external/internal factors, such as reward, punishment, attention, and emotional state affect learning and memory.

The Tonegawa Lab has been developing state-of-the-art genetic approaches to uncover the role of individual genes (neurotransmitter receptors, enzymes, etc.), spatially restricted cell types (via the Cre-loxP system), and specific hippocampal-entorhinal neural circuits in learning and memory processes using mice. These approaches combined with behavioral assays, in vitro electrophysiology by field and patch clamp recordings, in vivo electrophysiology by tetrodes and EEG, and in vivo optical imaging by two-photon microscopy have allowed us to link observed phenotypes with specific genetic manipulations.

Recently, the lab has led the field in the localization, visualization, and modulation of memory engram cells and their circuits through the combined use of transgenic and optogenetic methods such as channelrhodopsin and halorhodopsin. Engram technology has permitted manipulations of memory-associated cognitions and behaviors in health and neurological or psychiatric diseases.

Job Requirements

REQUIRED: a Ph.D. in neurosciences or related field; strong interpersonal and oral and written communication skills; and organizational skills for effectively managing own time and that of research assistants; and ability to prioritize research goals alongside non-research duties. Seek a highly motivated and self-driven candidate capable of working collaboratively in a research team of postdoctoral and predoctoral researchers while maintaining independent thinking and initiative. Experience or detailed familiarity with molecular genetics and optogenetic techniques preferred. Job #15809

In addition to submission of a cover letter and CV, please be prepared to arrange for the submission of three references, including one from a current or most recent PI.


MIT is an equal employment opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.